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It tethers vesicles to the plasma membrane, facilitating sound encoding.

Binding Sites: High-resolution structures revealed that multiple Ca 2+raised to the 2 plus power tm,cc,jp

This molecular mechanism allows the ear to convert sound into neural signals at incredibly high speeds. It tethers vesicles to the plasma membrane, facilitating

Upon binding, a "closed" conformation is adopted, where C-terminal domains (C2F, C2G) rearrange. 3. Key Findings in Synaptic Transmission Ca 2+raised to the 2 plus power a "closed" conformation is adopted

The protein utilizes C2 domains to bridge synaptic vesicles to the plasma membrane (plasma membrane being the "target membrane").

Structure and function of otoferlin, a synaptic protein of ... - PMC