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If you require cloning and simulation tools but do not have a budget, consider these reputable open-source or free alternatives: Course Licenses Offering SnapGene to your students as

: The SnapGene Viewer is a free version that allows you to open, visualize, and share annotated sequence files, though it lacks cloning simulation and editing tools. and share annotated sequence files

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: Another free software option for molecular biology and DNA sequence analysis. Pricing - SnapGene