: Brennan's father, played by Ryan O'Neal, makes an appearance as Brennan discusses her parenting plans.
: The team investigates human remains discovered inside a wine barrel during a tasting at a Virginia winery. The victim is Spencer Holt, an influential wine critic known for scathing reviews that could ruin a vineyard's reputation. [S4E25] The Critic in the Cabernet
: David Boreanaz previously made a cameo in Family Guy , and Stewie's appearance in Bones was considered a creative "exchange" between the shows. : Brennan's father, played by Ryan O'Neal, makes
: The hallucinations lead Brennan to realize Booth needs immediate medical attention. He is diagnosed with a brain tumor (an astrocytoma) and is rushed into surgery at the episode's end. Key Cast & Guest Stars Stewie Griffin : Voiced by Seth MacFarlane . : Brennan's father