In house music remixes like Mr Roland Magoo's, the upbeat yet soulful production typically emphasizes emotional healing and the "feeling" of the music rather than a complex narrative.
In many South African songs with this title, the lyrics express a soul's longing for peace, a higher power, or a return to one's roots.
The variation "Thula Moya Wam" specifically means "Be still, my soul," often used as a message of comfort during difficult times.
You can experience the soulful atmosphere of the track through this original mix: