Women generally have more flexible ligaments. While great for overall mobility, it can lead to instability at the base of the thumb (the "saddle joint"), causing the cartilage to wear down faster.
Sharp or dull pain at the base of the thumb when opening jars, turning doorknobs, or pulling zippers. mature ladies thumbs
Research suggests that declining estrogen levels during and after menopause can weaken collagen, making joints more vulnerable to wear and tear. Women generally have more flexible ligaments
The "Saddle" Struggle: Understanding Thumb Pain in Mature Women mature ladies thumbs