Targeted drugs recognize specific markers, typically proteins, that help cancer cells grow and spread.
Breast cancer treatment has undergone a significant transformation, evolving from broad-spectrum chemotherapy to highly targeted therapies that address specific molecular subtypes. Today, treatment is largely guided by such as hormone receptors (ER/PR) and the human epidermal growth factor receptor 2 (HER2), which allow for a "precision medicine" approach. 1. Hormone (Endocrine) Therapies breast cancer drugs
Tamoxifen is a cornerstone of HR+ treatment, approved for both pre- and post-menopausal patients to reduce recurrence risk. These drugs either lower hormone levels or block
Challenges and Opportunities in Metastatic Breast Cancer Treatments 2. Targeted Therapies
Hormone therapies are used for cancers that are hormone receptor-positive (HR+), meaning they use estrogen or progesterone to grow. These drugs either lower hormone levels or block receptors on cancer cells.
Drugs like Anastrozole (Arimidex) , Letrozole (Femara), and Exemestane (Aromasin) are primarily for postmenopausal women. They block the aromatase enzyme, which is necessary for making estrogen in the body. 2. Targeted Therapies